Samir Rahmani, FRCS (England), UK-Trained Laparoscopic, Bariatric & GI Surgeon, Dubai | Medically Reviewed: April 2026 Mounjaro causes diarrhea, constipation, and stomach pain because it activates GLP-1 receptors that slow gastric emptying and alter intestinal motility
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In the present study, GLP-1R expression in human endothelial cells was detected by RT-PCR and western blot analyses, and we demonstrated that GLP-1R at both mRNA and protein levels was detectable, albeit not very strong, in the human endothelial cells
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Common side effects and how to manage them Knowing what to expect and how to handle side effects prevents unnecessary protocol abandonment